Small, cancer-associated DNA circles "hitchhike" on chromosomes during cell division to spread efficiently to daughter cells ...

Life on Earth began simply. For billions of years, tiny microbes ruled the planet. Then, one day in deep time, something changed. Cells gained a nucleus, built inner compartments and learned to ...

Researchers created a highly efficient gene-editing method that fixes multiple DNA mutations in a single step. The breakthrough could revolutionize genetic medicine by making treatments for complex ...

The origins of complex, nucleated cellular life – everything from amoebas to humans – may date back a lot further in Earth's ...

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

When DNA breaks, cells must repair it accurately to prevent harmful mutations. Researchers have discovered that during a key ...

RNA, widely known from the COVID-19 vaccine, is not actually a "therapeutic agent," but a technology that delivers the ...

After two decades in the making, scientists have cracked the code on a drug that can repair DNA, setting the scene for a new ...

Cedars-Sinai scientists have created a new experimental drug called TY1 that helps the body repair damaged DNA and restore injured tissue. The discovery came from studying tiny molecular messages ...